Understanding brain networks in adolescents with anxiety and depression

Between- and Within-Person Heterogeneity in Adolescent Resting State Networks: Associations with Internalizing Psychopathology

NIH-funded research Temple Univ of the Commonwealth · NIH-10896957

This study is looking at how the connections in the brains of teenagers can change from person to person and over time, to help better understand anxiety and depression, so that treatments can be more personalized for each young person.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionTemple Univ of the Commonwealth NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10896957 on NIH RePORTER

What this research studies

This research investigates how brain connectivity patterns in adolescents can differ both between individuals and within the same individual over time. By using advanced imaging techniques, the study aims to identify specific brain network characteristics that may be linked to anxiety and depression in young people. The goal is to improve the accuracy of diagnoses and tailor interventions based on individual brain profiles, rather than relying solely on group averages. This approach could lead to more personalized treatment strategies for adolescents facing mental health challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who are experiencing symptoms of anxiety or depression.

Not a fit: Patients outside the age range of 12 to 20 or those without symptoms of anxiety or depression may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment options for adolescents suffering from anxiety and depression.

How similar studies have performed: Previous research has shown promise in using functional connectivity as a biomarker for mental health conditions, indicating that this approach may yield valuable insights.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.