Understanding brain network mechanisms in Fragile X Syndrome

Network mechanisms underlying core behavioral features in Fragile X Syndrome

NIH-funded research University of Oklahoma · NIH-10900221

This study is looking at how the brains of people with Fragile X Syndrome connect and work together, hoping to find out more about the challenges they face with thinking and behavior, so we can create better support and treatments for them.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Oklahoma NIH-funded
Lab location1 site (Norman, United States)
Project IDNIH-10900221 on NIH RePORTER

What this research studies

This research investigates the brain connectivity patterns in individuals with Fragile X Syndrome (FXS), a genetic condition that often leads to intellectual disabilities and autism spectrum disorder. By using electroencephalography (EEG), the study aims to identify specific disruptions in brain networks that relate to cognitive impairments and behavioral features associated with FXS. The goal is to differentiate between cognitive control issues and behavioral symptoms like sensory hypersensitivity and anxiety, which could lead to targeted interventions for affected individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Fragile X Syndrome, particularly those exhibiting cognitive impairments and behavioral challenges.

Not a fit: Patients without a diagnosis of Fragile X Syndrome or those who do not exhibit cognitive or behavioral issues related to the condition may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and targeted treatments for individuals with Fragile X Syndrome, enhancing their cognitive and behavioral outcomes.

How similar studies have performed: Previous research has shown promise in understanding brain connectivity in neurodevelopmental disorders, suggesting that this approach could yield valuable insights for Fragile X Syndrome as well.

Where this research is happening

Norman, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.