Understanding brain metastases and their treatment

NEUROPATHOLOGY/TISSUE BANK CORE

NIH-funded research Stanford University · NIH-10925252

This study is looking for patients with cancer that has spread to the brain to help create a collection of tissue samples, so researchers can learn more about how these tumors resist treatments and find better ways to help people respond to therapies.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10925252 on NIH RePORTER

What this research studies

This research focuses on brain metastases, which are cancerous growths that spread to the brain from other parts of the body. It aims to create a tissue bank of matched samples from primary cancers and their corresponding brain metastases to better understand how these tumors develop resistance to treatments like radiation and immunotherapy. By analyzing these samples, researchers hope to identify biomarkers that can predict patient responses to therapies and improve treatment strategies. Patients will contribute their tissue samples, which will be carefully processed and stored for future analysis.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with solid tumors that have metastasized to the brain.

Not a fit: Patients with primary brain tumors or those without any history of cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for patients with brain metastases, improving their survival and quality of life.

How similar studies have performed: Previous research has shown promise in using tissue banks to identify biomarkers for cancer treatment, indicating that this approach could be beneficial.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.