Understanding brain mechanisms that predict bipolar disorder in young adults
Reward, impulsive sensation seeking and emotional dysregulation: neural mechanisms underlying risk for bipolar disorder in young adults
This study is looking at how brain activity and structure can help spot young adults who might be at risk for bipolar disorder instead of just major depression, with the hope of finding ways to prevent these conditions from developing.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10989966 on NIH RePORTER |
What this research studies
This research investigates how certain brain activities and structures can help identify young adults at risk for bipolar disorder compared to major depressive disorder. By using advanced brain imaging techniques, the study aims to find objective neural markers that can predict future mental health issues. The goal is to develop new interventions that could delay or prevent the onset of these debilitating disorders by understanding the underlying neural mechanisms. Participants may undergo brain scans and assessments to help researchers gather data on emotional regulation and impulsivity.
Who could benefit from this research
Good fit: Ideal candidates for this research are young adults who may be experiencing symptoms of mood disorders or have a family history of bipolar disorder.
Not a fit: Patients who are not young adults or those who do not exhibit any symptoms of mood disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and prevention strategies for bipolar disorder in young adults.
How similar studies have performed: Previous research has shown promise in identifying neural markers for mood disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Phillips, Mary Louise — University of Pittsburgh at Pittsburgh
- Study coordinator: Phillips, Mary Louise
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.