NIH-funded research R21 grant

Understanding brain mechanisms behind walking difficulties in older adults who fall

Official title: Identifying potential cortical mechanisms responsible for gait impairment in older adult fallers

Funded at University of Massachusetts Amherst · NIH-10707873 · Data updated 2026-11-12

This study is looking at how certain parts of the brain affect walking and falling in older adults, using special imaging to see brain activity while they walk, with the hope of finding ways to help prevent falls and improve walking safety.

More Gait research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Massachusetts Amherst
NIH-funded
Lab location1 site (Hadley, United States)
Project startSeptember 30, 2022
Project endJune 30, 2025
Funding year2023
Award (this year)$189,869
NIH project number5R21AG075489-02
Project IDNIH-10707873 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults, particularly those who have experienced falls or have gait impairments.

Less likely to help

Patients who are younger than 21 years old or do not have any history of falls or gait issues may not benefit from this research.

What this research studies

This research investigates how specific areas of the brain, particularly the posterior parietal cortex, contribute to walking difficulties and fall risks in older adults. By using advanced imaging techniques, the study aims to measure brain activity during walking tasks that involve visual processing. The goal is to better understand the relationship between brain function and gait performance, which could lead to improved assessments and interventions for fall prevention in older adults. Participants will be observed while performing tasks that mimic real-life walking scenarios to gather comprehensive data.

Why it matters

Potential benefit: If successful, this research could lead to more effective fall prevention strategies for older adults, enhancing their safety and quality of life.

How similar studies have gone: Previous research has shown promising results in understanding brain mechanisms related to gait, but this specific focus on the posterior parietal cortex in older adults is relatively novel.

Where this research is happening

  • University of Massachusetts Amherst
    Hadley, United States
    Active

Researchers

  • Principal investigator: Martini, Douglas Nathaniel — University of Massachusetts Amherst
  • Study coordinator: Martini, Douglas Nathaniel

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.