Understanding brain markers to improve treatment for social anxiety disorder

Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety

['FUNDING_R01'] · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · NIH-10866401

This study is looking at how social anxiety disorder affects the brain and aims to find out which treatments, like therapy or medication, might work best for different people, so that everyone can get the most effective help possible.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorBOSTON UNIVERSITY (CHARLES RIVER CAMPUS) (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10866401 on ClinicalTrials.gov

What this research studies

This research investigates the neural mechanisms behind social anxiety disorder (SAD) and aims to identify reliable predictors of treatment outcomes. By utilizing advanced neuroimaging techniques and computational psychiatry, the study will analyze brain circuitry in individuals with SAD compared to healthy controls. The goal is to enhance personalized treatment approaches by understanding which patients are likely to respond to specific therapies, particularly cognitive behavioral therapy (CBT) and SSRIs. Participants will contribute to a better understanding of how different treatments affect brain function and how this knowledge can lead to more effective interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older who have been diagnosed with social anxiety disorder.

Not a fit: Patients who do not have social anxiety disorder or are under 21 years old may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatment options for individuals suffering from social anxiety disorder.

How similar studies have performed: Previous research has shown promise in identifying neural markers for treatment response in various mental health conditions, suggesting that this approach could yield valuable insights.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.