Understanding Brain Issues in Lupus
Anti-NMDA Receptor Antibodies in Adult Brain Dysfunction: Lessons from Lupus
['FUNDING_P01'] · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · NIH-11113397
This project aims to understand why people with lupus experience brain-related symptoms like memory problems, anxiety, and tiredness.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (nih funded) |
| Locations | 1 site (MANHASSET, UNITED STATES) |
| Trial ID | NIH-11113397 on ClinicalTrials.gov |
What this research studies
We are looking closely at how lupus affects the brain, causing symptoms like memory issues, anxiety, depression, and fatigue. Our team is studying both people with lupus and special mouse models to uncover the underlying causes of these problems. We hope to find new ways to treat these symptoms by identifying specific disease mechanisms and potential new therapies. We are also working to understand why these symptoms vary among patients, which could lead to more personalized care.
Who could benefit from this research
Good fit: Patients with Systemic Lupus Erythematosus experiencing cognitive impairment, anxiety, depression, or fatigue may be ideal candidates for related clinical efforts.
Not a fit: Individuals without Systemic Lupus Erythematosus or those not experiencing neuropsychiatric symptoms related to lupus may not directly benefit from this specific research.
Why it matters
Potential benefit: This work could lead to new treatments and better ways to manage brain-related symptoms for people living with lupus.
How similar studies have performed: This project builds upon ongoing, integrated studies, suggesting a foundation of prior work in this area.
Where this research is happening
MANHASSET, UNITED STATES
- FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH — MANHASSET, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DIAMOND, BETTY — FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
- Study coordinator: DIAMOND, BETTY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury, Affective Disorders