Understanding brain issues in children who survived leukemia treatment
Characterization of brain dysfunction during development in survivors of childhood acute lymphoblastic leukemia
['FUNDING_R01'] · ALBERT EINSTEIN COLLEGE OF MEDICINE · NIH-10813699
This study looks at how treatment for childhood leukemia might impact brain development and thinking skills in kids who survived the illness, helping to find out if they need extra support with things like memory and attention compared to their healthy friends.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALBERT EINSTEIN COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (BRONX, UNITED STATES) |
| Trial ID | NIH-10813699 on ClinicalTrials.gov |
What this research studies
This research investigates how treatment for childhood acute lymphoblastic leukemia (ALL) affects brain development and cognitive functioning in survivors. It aims to identify specific deficits in memory, attention, and sensory processing that may arise from chemotherapy. By using behavioral tests, brain imaging, and electrophysiological measures, the study compares the cognitive abilities of childhood cancer survivors to healthy peers. The findings will help develop tools to identify children who may need additional support due to treatment-related cognitive changes.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-21 who have survived acute lymphoblastic leukemia and undergone chemotherapy.
Not a fit: Patients who have not been treated for acute lymphoblastic leukemia or those with other unrelated cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for supporting cognitive development in children who have survived leukemia.
How similar studies have performed: Other research has shown that similar approaches can successfully identify cognitive deficits in childhood cancer survivors, indicating a promising avenue for this study.
Where this research is happening
BRONX, UNITED STATES
- ALBERT EINSTEIN COLLEGE OF MEDICINE — BRONX, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SUSSMAN, ELYSE S — ALBERT EINSTEIN COLLEGE OF MEDICINE
- Study coordinator: SUSSMAN, ELYSE S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.