Understanding brain injury and cognitive decline in older adults

Neuropathology Core

NIH-funded research University of California at Davis · NIH-10890766

This study is looking at how brain injuries can affect thinking skills in older adults, especially those from different backgrounds, and it will use advanced technology to better understand these effects while including a diverse group of participants.

Quick facts

Grant typeP30 center grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10890766 on NIH RePORTER

What this research studies

This research focuses on assessing and quantifying brain injuries that affect cognitive abilities in older adults, particularly those from diverse backgrounds. By utilizing advanced techniques such as digital pathology and machine learning, the study aims to analyze various brain pathologies and their impact on cognitive health. Participants will undergo comprehensive cognitive assessments and brain imaging, which will help identify risk and protective factors related to brain aging and dementia. The research emphasizes the inclusion of minority populations to ensure a broad understanding of these issues.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults experiencing cognitive decline or those at risk for Alzheimer's disease and related dementias, especially from diverse ethnic backgrounds.

Not a fit: Patients who are not experiencing cognitive decline or do not have a family history of Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of cognitive decline in older adults, particularly among diverse populations.

How similar studies have performed: Previous research has shown success in understanding cognitive decline through similar methodologies, particularly in diverse populations.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injuryAlzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.