Understanding brain injuries from sports-related concussions

Comprehensive White-matter Microstructure-informed Analytical Methods to Elucidate Neurobiological Mechanisms of Sports-related Concussion (SRC)

['FUNDING_R01'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-10814185

This study is looking into how sports-related concussions affect the brain to help us understand why some athletes take longer to recover, so we can improve how we support them during their healing process.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorINDIANA UNIVERSITY INDIANAPOLIS (nih funded)
Locations1 site (INDIANAPOLIS, UNITED STATES)
Trial IDNIH-10814185 on ClinicalTrials.gov

What this research studies

This research investigates the neurobiological mechanisms behind sports-related concussions (SRC) to better understand why some athletes experience prolonged recovery times. By utilizing advanced diffusion MRI techniques, the study aims to identify specific white matter changes associated with SRC, which are often difficult to detect. The goal is to improve assessment tools and management strategies for athletes suffering from concussions, ultimately enhancing their recovery process. The research will analyze clinical signs and symptoms in athletes to provide insights into the long-term consequences of SRC.

Who could benefit from this research

Good fit: Ideal candidates for this research are high school and collegiate athletes who have recently sustained a sports-related concussion.

Not a fit: Patients who have not experienced a concussion or those with chronic neurological conditions unrelated to sports injuries may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and management of concussions, helping athletes recover more effectively.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to assess brain injuries, indicating that this approach may yield valuable insights.

Where this research is happening

INDIANAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.