Understanding brain injuries and neurodegenerative disorders in Veterans
BLRD Research Career Scientist Award Application
This study is looking at how brain injuries and diseases like Alzheimer's and ALS affect Veterans, and it aims to find new ways to help by understanding the genes involved in these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA New Jersey Health Care System NIH-funded |
| Lab location | 1 site (East Orange, United States) |
| Project ID | NIH-10950346 on NIH RePORTER |
What this research studies
This research focuses on the increasing prevalence of traumatic brain injury and neurodegenerative disorders, such as Alzheimer's Disease and ALS, particularly among Veterans. The approach involves studying the molecular genetic aspects of neurons and glia to identify mechanisms that contribute to these conditions. By examining human CNS samples, animal models, and cultured neurons, the research aims to evaluate gene expression changes and interactions during neurodegeneration. The ultimate goal is to develop targeted treatments that can improve outcomes for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research include Veterans experiencing traumatic brain injuries or neurodegenerative conditions like Alzheimer's Disease or ALS.
Not a fit: Patients who do not have a history of traumatic brain injury or neurodegenerative disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve the quality of life for Veterans suffering from neurodegenerative disorders.
How similar studies have performed: Previous research has shown promise in understanding neurodegenerative mechanisms, suggesting that this approach could yield significant insights and advancements.
Where this research is happening
East Orange, United States
- VA New Jersey Health Care System — East Orange, United States (Active)
Researchers
- Principal investigator: Citron, Bruce a. — VA New Jersey Health Care System
- Study coordinator: Citron, Bruce a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.