Understanding brain health in people living with HIV
Biopsychosocial Phenotypes and Potential Mechanisms in CHARTER
This study is looking at how HIV can still affect brain health, including thinking and mood, even when people are getting good treatment, and it aims to find new ways to understand these issues by looking at different biological and social factors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10982516 on NIH RePORTER |
What this research studies
This research investigates the various brain-related complications that can occur in individuals living with HIV, even when they are receiving effective treatment. It focuses on cognitive and mood disorders, which are common among this population, and explores the role of inflammation and other biological factors in these conditions. By analyzing extensive data collected over nearly two decades, the study aims to develop new classifications of these disorders based on biological and psychosocial factors. Advanced techniques like machine learning will be used to categorize the data and identify distinct brain health profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who may be experiencing cognitive or mood-related issues.
Not a fit: Patients who are not living with HIV or those without any cognitive or mood disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cognitive and mood disorders in people living with HIV.
How similar studies have performed: Previous research has shown success in understanding CNS complications in HIV, but this approach aims to provide novel insights through advanced data analysis techniques.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Letendre, Scott L — University of California, San Diego
- Study coordinator: Letendre, Scott L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.