Understanding brain health in older adults living with HIV

Building Resources to Assess Impaired Neurocognition for Care and Research among Adults Aging with HIV (BRAIN Care HIV)

NIH-funded research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-10927454

This study is looking at how common brain health issues are in older adults with HIV, especially those over 50, to find out what might be causing these problems and how we can help improve their brain health and well-being.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionNew York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10927454 on NIH RePORTER

What this research studies

This research investigates the high rates of neurocognitive impairment (NCI) among older adults living with HIV, particularly focusing on those aged 50 and above. It aims to gather and analyze multimodal data, including demographic, medical, and inflammatory factors, to better understand the prevalence and risk factors associated with NCI in this population. By studying a diverse cohort in Malaysia over several years, the research seeks to identify specific needs and develop targeted interventions to improve brain health and overall well-being for aging individuals with HIV.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 50 and above who are living with HIV.

Not a fit: Patients who are younger than 50 years old or those without HIV may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of neurocognitive impairment in older adults with HIV, enhancing their quality of life.

How similar studies have performed: While there has been research on neurocognitive impairment in HIV, this study's focus on low- and middle-income countries is relatively novel and untested.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.