Understanding brain functions using advanced imaging techniques
Analysis of Integrated Brain Functions Using Hemogenetic Imaging
['FUNDING_R01'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-11015860
This study is exploring new ways to see how brain cells work and communicate with each other, using special tools that help scientists get a clearer picture of brain activity, which could lead to better understanding of how our brains affect our behavior and overall health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-11015860 on ClinicalTrials.gov |
What this research studies
This research investigates new imaging methods that allow scientists to visualize brain activity at a cellular level. By using genetically encoded molecular probes, known as NOSTICs, the study aims to improve the specificity of brain imaging techniques like fMRI. This approach enables researchers to differentiate between various cellular activities and blood flow changes, providing deeper insights into how different brain cells and circuits function together. The goal is to better understand the relationships between brain activity, behavior, and changes in gene expression.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological disorders or conditions that affect brain function.
Not a fit: Patients with conditions unrelated to brain function or those who do not have access to advanced imaging facilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise diagnostic tools and treatments for neurological conditions by enhancing our understanding of brain function.
How similar studies have performed: Other research has shown promising results using advanced imaging techniques, but this specific approach with NOSTICs is novel and untested.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JASANOFF, ALAN — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: JASANOFF, ALAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.