Understanding brain function in people with psychosis relapses
Striatal Function in Psychosis Relapse
This study is looking at how the brains of people with psychosis react when they have relapses while using long-acting injectable medications, to help us understand what happens in the brain during these tough times and how treatment can make a difference.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project ID | NIH-10854809 on NIH RePORTER |
What this research studies
This research investigates how the brain functions in individuals experiencing relapses of psychosis while being treated with long-acting injectable antipsychotics. By using advanced MRI techniques, the study aims to measure brain activity in specific areas related to psychosis and reward processing. The goal is to better understand the neurobiological mechanisms behind these relapses, which can significantly affect patients' lives and healthcare costs. Participants will be monitored for medication adherence, providing a clearer picture of how treatment impacts their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with psychotic disorders who are currently receiving long-acting injectable antipsychotics.
Not a fit: Patients who are not currently on long-acting injectable antipsychotics or those without a diagnosis of psychotic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for managing psychosis and reducing the frequency of relapses.
How similar studies have performed: Previous research has shown promise in understanding psychosis through neurobiological assessments, but this specific approach focusing on long-acting injectable antipsychotics is relatively novel.
Where this research is happening
Manhasset, United States
- Feinstein Institute for Medical Research — Manhasset, United States (Active)
Researchers
- Principal investigator: Rubio, Jose M — Feinstein Institute for Medical Research
- Study coordinator: Rubio, Jose M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.