Understanding brain factors that predict recovery from anorexia nervosa
Neural predictors of outcome during relapse prevention treatment for anorexia nervosa
This study is looking at how brain activity can help predict whether people with anorexia nervosa, who have recently gained weight, will do well in a special treatment program that helps change eating habits, so they can get the best support possible.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10582173 on NIH RePORTER |
What this research studies
This research investigates how brain activity and connectivity can predict treatment outcomes for individuals with anorexia nervosa (AN) who have recently normalized their weight. By utilizing fMRI technology, the study aims to identify neural predictors that may indicate the likelihood of relapse during a specialized treatment program called REACH+. This program focuses on changing habitual behaviors related to food intake through cognitive and behavioral therapies. The findings could help tailor more effective treatment strategies for patients struggling with AN.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who have been hospitalized for anorexia nervosa and have achieved weight normalization.
Not a fit: Patients who are under 21 years old or those who have not been hospitalized for anorexia nervosa may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment approaches that reduce relapse rates in patients with anorexia nervosa.
How similar studies have performed: Previous research in other psychiatric conditions has successfully identified neural predictors of treatment response, suggesting potential for similar success in this study.
Where this research is happening
New York, United States
- New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC — New York, United States (Active)
Researchers
- Principal investigator: Muratore, Alexandra Felicia — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Muratore, Alexandra Felicia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.