Understanding brain dysfunction in Alzheimer's and HIV patients
Official title: Dynamic Functional Mapping of Alzheimer's Spectrum and HIV-related Brain Dysfunction
Funded at Father Flanagan's Boys' Home · NIH-11091847 · Data updated 2026-11-12
This study is looking at how HIV might affect thinking and memory in people with Alzheimer's disease by exploring how their brains work, and it aims to help us understand these conditions better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Father Flanagan's Boys' Home NIH-funded |
| Lab location | 1 site (Boys Town, United States) |
| Project start | September 24, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $788,615 |
| NIH project number | 1R01NS141729-01 |
| Project ID | NIH-11091847 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults over 21 years old who are experiencing mild cognitive impairment, particularly those with a diagnosis of Alzheimer's disease or HIV.
✕Less likely to help
Patients who do not have cognitive impairments or are under 21 years old may not benefit from this research.
What this research studies
This research investigates the neurophysiological basis of cognitive impairments in patients with Alzheimer's disease and those infected with HIV. It aims to identify how HIV may contribute to cognitive decline by examining brain circuits and their dynamics. The study will utilize advanced techniques to quantify neural activity patterns, which could reveal important insights into the mechanisms of cognitive impairment. By focusing on the specific brain oscillations associated with different cognitive functions, the research seeks to enhance our understanding of these complex conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for patients suffering from cognitive impairments related to Alzheimer's and HIV.
How similar studies have gone: Previous research has successfully identified brain circuits involved in cognitive impairment, but this study aims to provide novel insights specifically related to HIV-related brain dysfunction.
Where this research is happening
-
Father Flanagan's Boys' Home
Boys Town, United States Active
Researchers
- Principal investigator: Wilson, Tony W — Father Flanagan's Boys' Home
- Study coordinator: Wilson, Tony W
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.