Understanding brain differences in women who abuse stimulants

Neurocognitive Abnormalities in Stimulant Abuse among High-Risk Women

NIH-funded research Lovelace Biomedical Research Institute · NIH-11089535

This study is looking at how stimulant drug use affects the brains of women in prison, especially those at high risk, to better understand their needs and help create better treatment options just for them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionLovelace Biomedical Research Institute NIH-funded
Lab location1 site (Albuquerque, United States)
Project IDNIH-11089535 on NIH RePORTER

What this research studies

This research investigates the neurobiological systems involved in stimulant abuse among high-risk women, particularly those who are incarcerated. By using a mobile MRI scanner, the study aims to analyze brain structure and function in relation to stimulant use and psychopathic traits. Participants will be categorized based on their history of stimulant use and psychological characteristics, allowing for a detailed examination of sex differences in brain circuitry and behavior. The findings could lead to improved treatment strategies tailored to the unique needs of women with substance use disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are incarcerated women with a history of stimulant abuse and varying levels of psychopathic traits.

Not a fit: Patients who do not have a history of stimulant abuse or are not incarcerated may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment options for women struggling with stimulant abuse and related psychiatric conditions.

How similar studies have performed: Previous studies have shown success in understanding neurobiological differences related to substance abuse, but this specific focus on incarcerated women is relatively novel.

Where this research is happening

Albuquerque, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.