Understanding brain development and its link to mental health risks

Mapping the functional organization of the cortex across development: The principal hierarchy and transdiagnostic psychopathology risk

NIH-funded research University of Pennsylvania · NIH-10996028

This study is looking at how changes in brain structure from childhood to adulthood might be linked to mental health issues, using special brain scans to help understand these connections and identify patterns that could show who might be at risk for mental illness.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10996028 on NIH RePORTER

What this research studies

This research investigates how the development of brain structures relates to mental health issues that can arise from childhood to adulthood. By using advanced imaging techniques like functional MRI, the study aims to map the organization of the brain's cortex and how it connects to various psychiatric conditions. The research will analyze large datasets that include brain imaging and clinical information to identify patterns that may indicate a risk for mental illness. This approach seeks to uncover the genetic and developmental factors that contribute to these risks.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals under 21 years old, particularly those with autism spectrum disorder or related developmental concerns.

Not a fit: Patients who are over 21 years old or do not have developmental disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and early identification of mental health risks in young individuals.

How similar studies have performed: Previous research has shown promising results in understanding brain development and its connection to mental health, indicating that this approach has potential for significant insights.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.