Understanding brain damage and recovery in early multiple sclerosis.
Cortical Demyelination and Repair in Early Multiple Sclerosis.
This study is looking at how brain damage happens and heals in young adults with early multiple sclerosis (MS), using special MRI scans to see these changes up close, with the hope of finding better ways to treat the condition and help manage disability.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10945252 on NIH RePORTER |
What this research studies
This research investigates how brain lesions develop and heal in individuals with early multiple sclerosis (MS), a condition that affects young adults and can lead to significant disability. By using advanced MRI techniques, the study aims to visualize these lesions in real-time and understand the immune responses involved in their formation and repair. The goal is to uncover the relationship between these cortical lesions and the progression of disability in MS patients, potentially leading to improved treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are young adults diagnosed with early multiple sclerosis who are experiencing cognitive or physical symptoms.
Not a fit: Patients with advanced multiple sclerosis or those who do not have a diagnosis of multiple sclerosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for patients with early multiple sclerosis, potentially reducing disability progression.
How similar studies have performed: Previous research has shown promise in understanding brain lesions in multiple sclerosis, but this study aims to explore novel aspects of cortical lesion dynamics that have not been extensively tested.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Beck, Erin Savner — Icahn School of Medicine at Mount Sinai
- Study coordinator: Beck, Erin Savner
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.