Understanding brain connectivity through advanced imaging techniques
Linking membrane voltage dynamics to fMRI measurement of functional connectivity in resting state and task related activities
This study is looking at how brain activity and blood flow work together to help us understand brain disorders like Alzheimer's disease, using special brain scans to see how different parts of the brain talk to each other when resting and during tasks.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11009493 on NIH RePORTER |
What this research studies
This research investigates how changes in brain activity and blood flow relate to each other using functional magnetic resonance imaging (fMRI). By studying brain connectivity in both resting states and during specific tasks, the project aims to uncover the underlying mechanisms of brain disorders, particularly Alzheimer's disease. The approach involves analyzing fluctuations in brain signals to better understand how different regions communicate and how these patterns may change in disease states. This could lead to improved methods for detecting and diagnosing brain disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias.
Not a fit: Patients with non-neurological conditions or those without cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the accuracy of diagnosing Alzheimer's disease and other brain disorders, leading to better patient outcomes.
How similar studies have performed: Previous research has shown promise in using fMRI to study brain connectivity, suggesting that this approach could yield valuable insights into Alzheimer's disease.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Meyer-Baese, Lisa M — Emory University
- Study coordinator: Meyer-Baese, Lisa M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.