Understanding brain connectivity in schizophrenia
Systems-Level Dysconnectivity in First Episode Psychosis
['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-11080228
This study is looking at how different parts of the brain work together in people who are having their first experience with psychosis, especially those with schizophrenia, to help us understand what might be causing their symptoms.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-11080228 on ClinicalTrials.gov |
What this research studies
This research investigates the brain's functional connectivity in individuals experiencing their first episode of psychosis, particularly focusing on schizophrenia. By examining how different brain regions communicate and integrate information, the study aims to uncover the underlying neural mechanisms that contribute to the symptoms of schizophrenia. Using advanced techniques like EEG and MEG, researchers will analyze brain activity and develop computational models to better understand these connections. This approach could lead to insights into how brain abnormalities affect perception and cognition in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing their first episode of psychosis, particularly those diagnosed with schizophrenia.
Not a fit: Patients with chronic schizophrenia or those not experiencing psychotic symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for individuals with schizophrenia.
How similar studies have performed: Previous research has shown promise in understanding brain connectivity in schizophrenia, suggesting that this approach could yield valuable insights.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: COFFMAN, BRIAN A — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: COFFMAN, BRIAN A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.