Understanding brain connectivity in autism and ADHD

Neural Substrates of Autism and ADHD: Reward Circuitry Connectivity and Individual Differences

['FUNDING_CAREER'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11054459

This study is looking at how the brain's reward system works in people with autism and ADHD compared to those without these conditions, hoping to find new insights that could improve diagnosis and treatment for everyone involved.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF SOUTHERN CALIFORNIA (nih funded)
Locations1 site (Los Angeles, UNITED STATES)
Trial IDNIH-11054459 on ClinicalTrials.gov

What this research studies

This research investigates how the brain's reward system is connected in individuals with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). By using advanced imaging techniques, the study aims to uncover the differences and similarities in brain connectivity patterns between those with these conditions and neurotypical individuals. The research will analyze large datasets to explore both categorical diagnoses and continuous symptoms, providing a comprehensive view of how these disorders manifest in the brain. This could lead to better understanding and potential new approaches for diagnosis and treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals aged 5 to 65 who have been diagnosed with ASD, ADHD, or both, as well as neurotypical controls.

Not a fit: Patients with conditions unrelated to ASD or ADHD, or those outside the specified age range, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic methods and targeted interventions for individuals with autism and ADHD.

How similar studies have performed: Previous research has shown promising results in understanding brain connectivity in similar populations, indicating that this approach has potential for success.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Attention deficit hyperactivity disorder, Autistic Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.