Understanding Brain Connections with MRI
Biophysical Basis of Functional Connectivity by MRI
['FUNDING_R01'] · VANDERBILT UNIVERSITY MEDICAL CENTER · NIH-11114071
This research helps us better understand how different parts of the brain communicate using MRI scans.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-11114071 on ClinicalTrials.gov |
What this research studies
Our goal is to confirm if MRI scans can accurately show how brain regions connect and work together. We are also looking at what factors might change these connections and how these changes relate to brain function and behavior. This work uses advanced MRI techniques in animal models to ensure that the MRI methods we use for people are as accurate and reliable as possible. By improving our understanding of these connections, we hope to make MRI a more powerful tool for understanding the human brain.
Who could benefit from this research
Good fit: This foundational research does not directly involve patients, but its findings will ultimately benefit individuals undergoing MRI scans for brain-related conditions.
Not a fit: Patients seeking immediate treatment or direct clinical intervention would not find direct benefit from participating in this foundational research.
Why it matters
Potential benefit: If successful, this work could lead to more accurate and reliable MRI scans for understanding brain function and diagnosing conditions in humans.
How similar studies have performed: This research builds upon existing knowledge of brain imaging but focuses on a novel validation approach using invasive techniques in animal models to improve human fMRI interpretation.
Where this research is happening
NASHVILLE, UNITED STATES
- VANDERBILT UNIVERSITY MEDICAL CENTER — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GORE, JOHN C — VANDERBILT UNIVERSITY MEDICAL CENTER
- Study coordinator: GORE, JOHN C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.