Understanding Brain Connections in Conditions like Autism
Developmental Mechanisms of Fine-scale Cortico-cortical Circuit Formation
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA SANTA CRUZ · NIH-11083063
This work explores how brain connections form, which helps us understand conditions like autism and develop new ways to help patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA SANTA CRUZ (nih funded) |
| Locations | 1 site (SANTA CRUZ, UNITED STATES) |
| Trial ID | NIH-11083063 on ClinicalTrials.gov |
What this research studies
Our brains have special connections called cortico-cortical projection neurons that help different areas of the brain talk to each other for things like processing senses and making movements. When these connections don't form correctly, it can lead to conditions such as autism, dyslexia, and schizophrenia. This project aims to discover the exact steps and molecules involved in building these brain connections at a very detailed level. By understanding these fundamental processes, we hope to uncover the root causes of neurodevelopmental disorders and pave the way for new treatments.
Who could benefit from this research
Good fit: Patients with neurodevelopmental disorders, particularly those with autism, could ultimately benefit from future therapies developed based on the foundational knowledge gained from this research.
Not a fit: Patients without neurodevelopmental disorders or those seeking immediate treatment options may not directly benefit from this basic science research.
Why it matters
Potential benefit: If successful, this work could provide crucial insights into the genetic and molecular causes of neurodevelopmental disorders, leading to the development of new therapies for patients with conditions like autism.
How similar studies have performed: This research seeks to gain mechanistic insights into fundamental brain development, representing a novel approach to understanding the underpinnings of neurodevelopmental disorders.
Where this research is happening
SANTA CRUZ, UNITED STATES
- UNIVERSITY OF CALIFORNIA SANTA CRUZ — SANTA CRUZ, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KIM, EUISEOK J — UNIVERSITY OF CALIFORNIA SANTA CRUZ
- Study coordinator: KIM, EUISEOK J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autistic Disorder