Understanding brain complications in sickle cell disease
Mentoring in Patient-Oriented Research focused on Neurological Complications of Sickle Cell Disease
This study is looking at how sickle cell anemia can affect the brain, especially in adults, by checking for silent strokes and other brain injuries, and it aims to help improve care for patients by understanding these issues better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10664964 on NIH RePORTER |
What this research studies
This research investigates the neurological complications associated with sickle cell anemia, particularly focusing on silent cerebral infarcts and strokes in adults. The project aims to identify the incidence of these brain injuries and assess risk factors using advanced brain imaging techniques. By mentoring a diverse group of trainees, the research seeks to enhance understanding of the mechanisms behind brain injury in sickle cell patients and improve patient outcomes. The study involves collaboration across multiple centers to gather comprehensive data on this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 18 and older who have been diagnosed with sickle cell anemia.
Not a fit: Patients who do not have sickle cell disease or are under 18 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for neurological complications in patients with sickle cell disease.
How similar studies have performed: Previous research has shown promising results in understanding brain complications in sickle cell disease, indicating that this approach has potential for significant advancements.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Jordan, Lori Chaffin — Vanderbilt University Medical Center
- Study coordinator: Jordan, Lori Chaffin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.