Understanding brain circuits involved in decision-making
Multimodal Characterization of Prefrontal and Premotor Circuits Underlying Perceptual Decision Making in Therhesus Monkey
This study is looking at how certain brain cells in monkeys help them make decisions based on what they see and hear, which could help us understand how brain injuries or mental health issues affect decision-making in people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10864977 on NIH RePORTER |
What this research studies
This research investigates how specific neurons and their connections in the brain's prefrontal and premotor areas influence decision-making processes. By studying rhesus monkeys, the researchers aim to uncover how these brain regions interact and how their activity relates to making choices based on sensory information. The study employs advanced techniques such as neurophysiology, optical stimulation, and neuron analysis to explore these relationships in detail. This work could provide insights into how decision-making can be affected by brain injuries or mental health conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with acquired brain injuries or conditions that affect decision-making abilities.
Not a fit: Patients with conditions unrelated to decision-making processes or those who do not have brain injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals with decision-making impairments due to brain injuries or mental illnesses.
How similar studies have performed: Previous research has shown promising results in understanding brain circuits related to decision-making, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Luebke, Jennifer I — Boston University Medical Campus
- Study coordinator: Luebke, Jennifer I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.