Understanding brain circuits involved in cocaine addiction
Novel Addiction Neurocircuits in Cocaine Taking
This study is looking at how certain parts of the brain work together to affect cocaine addiction, with the goal of finding new ways to help people who are trying to overcome their cocaine use.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project ID | NIH-11012257 on NIH RePORTER |
What this research studies
This research investigates the neural circuits in the brain that influence cocaine addiction, specifically focusing on the ventral pallidum, a region associated with reward and motivation. By exploring how these circuits interact with other brain areas, the study aims to identify new targets for medications that could help individuals struggling with cocaine use disorder. The research employs advanced techniques such as behavioral economics and neuroanatomical tracing to map these connections and understand their role in addiction. This approach seeks to uncover mechanisms that could lead to better treatment options for those affected by cocaine addiction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cocaine use disorder who are seeking treatment options.
Not a fit: Patients who do not have a history of cocaine use or those with other substance use disorders unrelated to cocaine may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new medications that effectively treat cocaine use disorder.
How similar studies have performed: Previous research has shown promise in targeting neural circuits for addiction treatment, suggesting that this approach could yield significant advancements.
Where this research is happening
Galveston, United States
- University of Texas Med Br Galveston — Galveston, United States (Active)
Researchers
- Principal investigator: Hommel, Jonathan Dean — University of Texas Med Br Galveston
- Study coordinator: Hommel, Jonathan Dean
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.