Understanding brain circuits involved in addiction
Isolation of brain reward circuits using peptidergic systems
This study is looking at how certain brain cells work in addiction, hoping to find new ways to help people struggling with addiction by understanding their unique brain wiring better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11059071 on NIH RePORTER |
What this research studies
This research investigates the complex brain circuits that are involved in addiction by focusing on specific types of neurons and their unique properties. Using advanced genetic techniques, the study aims to identify how different genetic signatures and ion channels in these neurons contribute to their function and connectivity. By understanding these mechanisms, the research seeks to uncover new therapeutic targets for treating addictive disorders. Patients may benefit from insights that could lead to more effective treatments for addiction based on individual brain circuitry.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with addiction or those at risk of developing addictive disorders.
Not a fit: Patients who do not have any history of addiction or related disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for addiction.
How similar studies have performed: Other research has shown promise in understanding brain circuits related to addiction, but this approach may offer novel insights into specific neuronal functions.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Zweifel, Larry S — University of Washington
- Study coordinator: Zweifel, Larry S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.