Understanding Brain Circuit Changes in Schizophrenia
An integrative computational interrogation of circuit dysfunction inschizophrenia via neural timescales
This project looks at brain activity patterns in people with schizophrenia to better understand the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11113881 on NIH RePORTER |
What this research studies
Schizophrenia is a complex illness, and this project aims to uncover its underlying causes by looking at brain activity. Researchers are using advanced computer methods to analyze brain scans from many individuals, including those with schizophrenia and other conditions. They are specifically focusing on "neural timescales," which are patterns of brain activity that might show imbalances in brain circuits. By studying these patterns, we hope to connect genetic factors, brain development, and symptoms of schizophrenia. This work could lead to new ways to understand and eventually treat the condition.
Who could benefit from this research
Good fit: This project primarily uses existing data from individuals with schizophrenia, other disorders, and healthy individuals.
Not a fit: Patients not diagnosed with schizophrenia or related conditions may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could provide a clearer understanding of the brain changes in schizophrenia, potentially leading to new targets for treatments.
How similar studies have performed: This project extends prior work on neural timescales in schizophrenia, building on existing findings while introducing novel computational approaches.
Where this research is happening
New York, United States
- New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC — New York, United States (Active)
Researchers
- Principal investigator: Horga, Guillermo — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Horga, Guillermo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.