Understanding brain changes related to cognitive impairment

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NIH-funded research University of California at Davis · NIH-10929349

This study is looking at how certain changes in the brain might lead to memory and thinking problems, and it's for anyone interested in understanding more about what causes cognitive decline.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10929349 on NIH RePORTER

What this research studies

This research focuses on identifying the biological and anatomical factors that contribute to cognitive decline, particularly through the lens of white matter injury in the brain. By utilizing advanced neuroimaging techniques, fluid biomarkers, and genetic data, the study aims to gather comprehensive information from a diverse group of participants. The goal is to create a centralized repository that will facilitate the analysis and sharing of this data, ultimately enhancing our understanding of cognitive impairment and its underlying mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing cognitive complaints, particularly those from diverse backgrounds.

Not a fit: Patients without cognitive complaints or those not at risk for Alzheimer's disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for cognitive impairment and Alzheimer's disease.

How similar studies have performed: Previous research has shown promise in using similar approaches to understand cognitive decline, indicating potential for success in this study.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.