Understanding brain changes in preschoolers with autism
Neural signatures of outcome in preschoolers with autism
['FUNDING_R01'] · CHILD MIND INSTITUTE, INC. · NIH-10442708
This study looks at how the brains of preschoolers with autism develop while they sleep and how these changes might relate to their behaviors as they grow, helping us find early signs that could guide better support and treatment for them.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CHILD MIND INSTITUTE, INC. (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10442708 on ClinicalTrials.gov |
What this research studies
This research investigates how brain development in preschoolers with autism spectrum disorder (ASD) relates to their behavior over time. By using advanced MRI techniques during natural sleep, the study aims to identify early brain patterns that may predict future functioning in children with ASD. The focus is on understanding changes in specific brain circuits and how these changes correlate with repetitive behaviors that are common in autism. This longitudinal approach will help in identifying early markers that can inform treatment and support strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are preschool-aged children (2-3 years) diagnosed with autism spectrum disorder.
Not a fit: Patients who are older than 3 years or do not have a diagnosis of autism spectrum disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate prognostic markers for children with autism, improving individualized treatment plans.
How similar studies have performed: Previous research has shown promise in using neuroimaging techniques to understand brain-behavior relationships in autism, indicating that this approach could yield valuable insights.
Where this research is happening
NEW YORK, UNITED STATES
- CHILD MIND INSTITUTE, INC. — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DI MARTINO, ADRIANA — CHILD MIND INSTITUTE, INC.
- Study coordinator: DI MARTINO, ADRIANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.