Understanding Brain Changes in Parkinson's
Parkinsonism-Related Changes in Activity of Cortical Projection Neurons in Monkeys
['FUNDING_OTHER'] · EMORY UNIVERSITY · NIH-11174567
This project aims to better understand how brain activity changes in Parkinson's disease, which could help explain movement difficulties.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11174567 on ClinicalTrials.gov |
What this research studies
Parkinson's disease causes a loss of dopamine in the brain, leading to unusual brain activity that affects movement. We want to learn more about these specific changes in the brain's motor control areas, which are currently not well understood. By studying how certain brain cells in these areas behave in a model of Parkinson's, we hope to uncover why symptoms like slowness of movement occur. This work also looks at how current treatments for Parkinson's might affect these brain activity patterns.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but focuses on understanding the brain changes relevant to individuals with Parkinson's disease.
Not a fit: Patients seeking immediate new treatments or direct clinical intervention will not find it in this basic science project.
Why it matters
Potential benefit: This work could lead to a deeper understanding of Parkinson's disease, potentially guiding the development of new or improved treatments for movement symptoms.
How similar studies have performed: Previous work has shown changes in brain activity in similar models, but this project aims to specifically identify and characterize activity in particular brain cells and the effects of therapies.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GALVAN, ADRIANA — EMORY UNIVERSITY
- Study coordinator: GALVAN, ADRIANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.