Understanding brain changes in early psychosis
Neuroprogression across the Psychosis Spectrum in the Early Course of Illness
['FUNDING_R01'] · MCLEAN HOSPITAL · NIH-10560521
This study is looking at how the brains of people with early signs of psychosis change over time, so we can better understand their experiences and find new ways to help them feel better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MCLEAN HOSPITAL (nih funded) |
| Locations | 1 site (BELMONT, UNITED STATES) |
| Trial ID | NIH-10560521 on ClinicalTrials.gov |
What this research studies
This research investigates how the brain changes over time in individuals experiencing early symptoms of psychosis. By using advanced imaging techniques and neurocognitive testing, the study aims to track these changes in a group of patients over several years. The goal is to identify critical periods of neuroprogression that could inform the development of targeted treatments. This approach seeks to enhance our understanding of the timing and nature of these changes to improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are in the early stages of experiencing psychosis.
Not a fit: Patients who are not experiencing symptoms of psychosis or are in later stages of the illness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective interventions that prevent further decline in patients with early psychosis.
How similar studies have performed: Previous research has shown promising results in understanding neuroprogression in psychosis, but this study aims to provide a more detailed and longitudinal perspective.
Where this research is happening
BELMONT, UNITED STATES
- MCLEAN HOSPITAL — BELMONT, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEWANDOWSKI, KATHRYN EVE — MCLEAN HOSPITAL
- Study coordinator: LEWANDOWSKI, KATHRYN EVE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.