Understanding Brain Changes in Children with Type 1 Diabetes
Determinants of Neurocognitive Complications in T1D
['FUNDING_U01'] · UNIVERSITY OF COLORADO DENVER · NIH-11168849
This research helps us learn why children with type 1 diabetes sometimes have subtle changes in their thinking and brain development.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11168849 on ClinicalTrials.gov |
What this research studies
Children with type 1 diabetes can experience small changes in how their brain works and develops, which can make managing their condition harder over time. We don't fully understand why these changes happen, but factors like low blood sugar, high blood sugar, and diabetic ketoacidosis might play a role. Our team at the University of Colorado is joining a large group of researchers to follow children with type 1 diabetes for up to three years after their diagnosis. We will collect information to better understand how these factors affect their thinking and well-being.
Who could benefit from this research
Good fit: This research is looking for pre-pubertal children who have recently been diagnosed with type 1 diabetes.
Not a fit: Adults or children without type 1 diabetes would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to better ways to protect the brain health and thinking abilities of children living with type 1 diabetes.
How similar studies have performed: While the exact causes are not fully understood, other studies have suggested links between blood sugar control and brain health in type 1 diabetes, and this research aims to build on that knowledge.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: REWERS, MARIAN J — UNIVERSITY OF COLORADO DENVER
- Study coordinator: REWERS, MARIAN J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brittle Diabetes Mellitus, Childhood diabetes