Understanding brain changes in children with one-sided cerebral palsy
Multimodal Characterization of Cerebral Reorganization in Children with Unilateral Cerebral Palsy
This study is looking at how the brains of children with unilateral cerebral palsy adapt, so we can better understand their unique challenges with using their affected hand and create personalized therapies to help them improve their hand function and daily activities.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10816887 on NIH RePORTER |
What this research studies
This research investigates how the brain adapts in children with unilateral cerebral palsy (UCP), a condition that affects movement and coordination due to brain injury. By using advanced imaging techniques, the study aims to identify unique patterns of brain connectivity that relate to the challenges these children face in using their affected hand. The goal is to tailor therapies to each child's specific brain characteristics, potentially improving their hand function and overall participation in daily activities. This approach emphasizes the importance of personalized treatment based on individual brain reorganization.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years diagnosed with unilateral cerebral palsy.
Not a fit: Patients with bilateral cerebral palsy or those outside the specified age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective therapies that enhance hand function in children with unilateral cerebral palsy.
How similar studies have performed: Previous research has shown promise in using multimodal approaches to understand brain plasticity in children with movement disorders, suggesting potential for success in this area.
Where this research is happening
Boston, United States
- Boston University (Charles River Campus) — Boston, United States (Active)
Researchers
- Principal investigator: Ferre, Claudio Luis — Boston University (Charles River Campus)
- Study coordinator: Ferre, Claudio Luis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.