Understanding brain changes in Alzheimer's disease through advanced statistical modeling
Statistical methods for longitudinal integrated mechanistic modeling of multiview data
This study is looking at how changes in the brain over time can help us understand Alzheimer's disease and similar conditions, using different types of information like brain scans and genetics, to find better ways to treat these diseases just for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10843282 on NIH RePORTER |
What this research studies
This research investigates how brain changes over time can be modeled using advanced statistical methods, focusing on Alzheimer's disease and related conditions. By analyzing various types of data, including neuroimaging, genetic information, and environmental factors, the study aims to uncover the complex relationships that contribute to neurodevelopment and neurodegeneration. The goal is to develop new methodologies that can integrate and analyze large datasets to provide insights into the mechanisms of these diseases, ultimately leading to more personalized treatment approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing symptoms of Alzheimer's disease or those at risk due to genetic or environmental factors.
Not a fit: Patients with non-neurodegenerative conditions or those not affected by Alzheimer's disease may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for Alzheimer's disease and related neurodegenerative conditions.
How similar studies have performed: Previous research has shown promise in using integrated data analysis for understanding complex diseases, indicating that this approach could yield valuable insights.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Zhao, Yi — Indiana University Indianapolis
- Study coordinator: Zhao, Yi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.