Understanding brain changes in Alzheimer's disease and related dementias
Core D: Neuropathology Core
['FUNDING_P30'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10883734
This study is looking into what causes Alzheimer's disease and similar conditions by examining brain tissue from people who have passed away, hoping to find new clues beyond the usual focus on beta-amyloid, to help improve our understanding of dementia.
Quick facts
| Phase | ['FUNDING_P30'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-10883734 on ClinicalTrials.gov |
What this research studies
This research focuses on investigating the biological mechanisms behind Alzheimer's disease and related dementias by utilizing the University of Michigan Brain Bank. It aims to identify and understand factors beyond beta-amyloid that contribute to brain dysfunction and neurodegeneration. The study will collect and analyze post-mortem brain tissue and associated clinical data from participants, facilitating innovative research through collaboration with various institutions. By providing essential resources and expertise, the project seeks to advance knowledge in the field of dementia.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias who are willing to contribute post-mortem biospecimens.
Not a fit: Patients who do not have a diagnosis of Alzheimer's disease or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and potential treatments for Alzheimer's disease and related dementias.
How similar studies have performed: Previous research has shown success in understanding neurodegenerative diseases through similar approaches, making this a promising area of investigation.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIEBERMAN, ANDREW P — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: LIEBERMAN, ANDREW P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease and related dementia, Alzheimer's disease and related disorders