Understanding brain changes and treatment responses in Fragile X Syndrome

Network Mechanisms, Biomarkers and Pharmacology of Fragile X Syndrome in Humans

['FUNDING_OTHER'] · CINCINNATI CHILDRENS HOSP MED CTR · NIH-10907668

This study is looking at how the brain works in people with Fragile X Syndrome to see how it affects their senses and thinking, and it also wants to find out if certain medications can help improve these brain functions.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorCINCINNATI CHILDRENS HOSP MED CTR (nih funded)
Locations1 site (CINCINNATI, UNITED STATES)
Trial IDNIH-10907668 on ClinicalTrials.gov

What this research studies

This research investigates the brain's electrical activity and its relationship to sensory and cognitive functions in individuals with Fragile X Syndrome (FXS). By using advanced techniques like EEG, the study aims to identify specific neurophysiological changes associated with FXS and how these changes affect behavior and cognition. The research also explores how different medications may influence these brain alterations, providing insights into potential treatment options. Participants will contribute to a better understanding of the condition and help develop targeted therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Fragile X Syndrome, particularly those under 21 years of age.

Not a fit: Patients without a diagnosis of Fragile X Syndrome or those over 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for individuals with Fragile X Syndrome, enhancing their quality of life.

How similar studies have performed: Previous research has shown promising results in understanding neurophysiological changes in FXS, indicating that this approach has potential for significant advancements.

Where this research is happening

CINCINNATI, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.