Understanding brain and spinal cord connections in Multiple Sclerosis

Microstructure and connectivity modeling from the cortex to the spinal cord in Multiple Sclerosis

NIH-funded research Vanderbilt University Medical Center · NIH-11045630

This study is looking at new ways to use advanced MRI technology to better understand how Multiple Sclerosis affects the brain and spinal cord, which could lead to better tools for diagnosing and treating the condition.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-11045630 on NIH RePORTER

What this research studies

This research focuses on using advanced diffusion magnetic resonance imaging (MRI) to explore the microstructure and connectivity between the brain and spinal cord in patients with Multiple Sclerosis (MS). The goal is to develop new methods to simultaneously analyze these structures, which could help in understanding the extent of neurological damage caused by the disease. By addressing current limitations in imaging techniques, the research aims to provide a clearer picture of how MS affects the central nervous system. Patients may benefit from improved diagnostic tools and treatment strategies based on the findings.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Multiple Sclerosis who are undergoing treatment or monitoring for their condition.

Not a fit: Patients with neurological disorders other than Multiple Sclerosis may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to better diagnostic methods and treatment options for patients with Multiple Sclerosis.

How similar studies have performed: While there have been advancements in MRI techniques, this specific approach to simultaneously analyze brain and spinal cord connectivity in MS is relatively novel and has not been extensively tested.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
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Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.