Understanding Brain and Mood Changes in Lupus
Clinical Core
['FUNDING_P01'] · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · NIH-11113401
This project creates the essential support system for studies that aim to better understand how lupus affects thinking and mood in people.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (nih funded) |
| Locations | 1 site (MANHASSET, UNITED STATES) |
| Trial ID | NIH-11113401 on ClinicalTrials.gov |
What this research studies
This core provides the crucial framework for connecting studies that use animal models with those involving human participants. It will manage a central database to help identify groups of patients with neurocognitive and behavioral features similar to those seen in our mouse models. The core also supports the human studies by coordinating patient recruitment, ensuring participants meet all requirements, and tracking their progress through long-term assessments. Additionally, it handles the collection and shipment of biological samples to the appropriate labs, while also ensuring all safety and regulatory guidelines are followed.
Who could benefit from this research
Good fit: Ideal candidates for the related studies would be adults aged 21 and older who have Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) or healthy individuals willing to participate as controls.
Not a fit: Patients who do not have NPSLE or related cognitive and affective impairments would likely not directly benefit from participation in the specific studies supported by this core.
Why it matters
Potential benefit: If successful, this foundational work could lead to a deeper understanding of how lupus impacts the brain, potentially paving the way for new ways to help patients with cognitive and mood challenges.
How similar studies have performed: This project establishes the infrastructure for future studies, rather than testing a specific intervention, so its success is measured by its ability to facilitate robust research.
Where this research is happening
MANHASSET, UNITED STATES
- FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH — MANHASSET, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ARANOW, CYNTHIA — FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
- Study coordinator: ARANOW, CYNTHIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.