Understanding brain and genetic factors in addiction through shared data

ENIGMA- Addiction: Pooling of Existing Datasets to Identify Brain and Genetic Correlates of Addiction, Next Steps

NIH-funded research University of Vermont & St Agric College · NIH-11103394

This study is looking at how brain structure and genes might affect addiction by combining information from over 24,000 people, which could help us find better ways to treat addiction and create personalized support for those who need it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Vermont & St Agric College NIH-funded
Lab location1 site (Burlington, United States)
Project IDNIH-11103394 on NIH RePORTER

What this research studies

This research aims to explore the brain structure and genetic factors associated with addiction by pooling existing datasets from various institutions worldwide. By combining neuroimaging and genomic data from over 24,000 participants, the study seeks to enhance the understanding of addiction and improve treatment approaches. Patients may benefit from insights gained through this large-scale analysis, which could lead to more effective interventions tailored to individual needs. The research utilizes advanced statistical methods to analyze the data and identify significant patterns related to addiction.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals aged 21 and older who have experienced addiction or addictive disorders.

Not a fit: Patients who do not have a history of addiction or related disorders may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals struggling with addiction.

How similar studies have performed: Previous research using similar data pooling approaches has shown success in identifying brain correlates of various conditions, indicating a promising avenue for understanding addiction.

Where this research is happening

Burlington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virusaddictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.