Understanding brain activity to improve mental health treatments

Novel multimodal neural, physiological, and behavioral sensing and machine learning for mental states

['FUNDING_OTHER'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11017073

This study is looking at how brain activity connects to our feelings and thoughts, with the goal of creating better, personalized treatments for mental health issues, and it involves patients sharing their experiences and data through wearables during social situations.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF SOUTHERN CALIFORNIA (nih funded)
Locations1 site (Los Angeles, UNITED STATES)
Trial IDNIH-11017073 on ClinicalTrials.gov

What this research studies

This research investigates how brain activity relates to mental states, aiming to uncover the neural mechanisms behind emotional functioning. It employs advanced techniques like intracranial EEG to monitor brain activity over multiple days while also integrating physiological and behavioral data. By addressing the challenges of simultaneous monitoring and using machine learning, the study seeks to develop personalized therapies for various mental disorders. Patients may be involved in providing data through wearables and self-reports during social interactions.

Who could benefit from this research

Good fit: Ideal candidates include individuals with mental health conditions such as anxiety, autism spectrum disorders, or other emotional regulation issues.

Not a fit: Patients with severe cognitive impairments or those unable to participate in behavioral assessments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatments for mental health disorders.

How similar studies have performed: While the integration of multiple monitoring modalities is challenging, similar approaches in neuroscience have shown promise in enhancing our understanding of mental health.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: autism spectral disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.