Understanding brain activity through advanced imaging techniques in rodents
Official title: Computational volumetric one-photon voltage imaging in rodents
Funded at Rockefeller University · NIH-10835427 · Data updated 2026-11-12
This study is working on a new way to see how groups of brain cells communicate with each other in awake rodents, which could help us understand how the brain works during different tasks and improve our knowledge of brain development.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rockefeller University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 30, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $259,095 |
| NIH project number | 1R21EY035958-01 |
| Project ID | NIH-10835427 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with neurological conditions that affect brain function, as well as researchers in neuroscience.
✕Less likely to help
Patients with conditions unrelated to brain function or those not involved in neuroscience research may not receive direct benefits from this research.
What this research studies
This research focuses on developing a new imaging system to capture the electrical activity of large groups of neurons in the brains of awake, behaving rodents. By utilizing advanced genetically encoded voltage indicators, the project aims to overcome current limitations in imaging techniques that restrict the ability to observe neuronal communication in three dimensions. The goal is to create a tool that can record neuronal activity at both high speed and across a wide area, providing insights into how brain networks function during cognitive tasks. This could lead to a better understanding of brain development and its computational capabilities.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain function and potentially inform treatments for neurological disorders.
How similar studies have gone: Other research has shown promise in using advanced imaging techniques to study brain activity, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Rockefeller University
New York, United States Active
Researchers
- Principal investigator: Oenol-Noebauer, Tobias — Rockefeller University
- Study coordinator: Oenol-Noebauer, Tobias
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.