Understanding brain activity related to smoking lapses
Linking brain network dynamics to imminent smoking lapse risk and behavior
This study is looking at how the brain works when adults are trying to quit smoking and might be tempted to smoke again, to help find better ways to support people in staying smoke-free.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project ID | NIH-10897033 on NIH RePORTER |
What this research studies
This research investigates the brain dynamics that contribute to lapses in smoking cessation among adults. Using functional magnetic resonance imaging (fMRI), the study aims to identify how brain activity changes in the moments leading up to a smoking lapse, particularly during periods of nicotine abstinence. Participants will undergo a 12-hour abstinence period before engaging in a specially designed fMRI task that simulates the decision-making process around smoking. The findings could help in developing strategies to prevent relapse in individuals trying to quit smoking.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are currently trying to quit smoking or have recently quit.
Not a fit: Patients who do not smoke or are not attempting to quit smoking may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved interventions for preventing smoking relapse, ultimately aiding individuals in their efforts to quit smoking.
How similar studies have performed: Previous research using fMRI to study smoking behavior has shown promise, indicating that this approach could yield valuable insights into smoking lapses.
Where this research is happening
University Park, United States
- Pennsylvania State University, the — University Park, United States (Active)
Researchers
- Principal investigator: Wilson, Stephen Jeffrey — Pennsylvania State University, the
- Study coordinator: Wilson, Stephen Jeffrey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.