Understanding brain activity in children with Fragile X Syndrome

FX ENTRAIN: Perturbation of neurodynamics underlying sensory hyperarousal and statistical learning in Youth with FXS

NIH-funded research Cincinnati Childrens Hosp Med Ctr · NIH-10899435

This study looks at how the brains of children with Fragile X Syndrome respond to sounds, hoping to understand their unique brain activity better, which could help find new ways to support their learning and sensory experiences.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCincinnati Childrens Hosp Med Ctr NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-10899435 on NIH RePORTER

What this research studies

This research investigates how brain activity differs in children with Fragile X Syndrome (FXS), particularly focusing on their responses to auditory stimuli. By analyzing brain waves through EEG, the study aims to identify the unique neurodynamics that contribute to sensory and cognitive challenges faced by these children. The research will explore both group trends and individual variations in brain function, which may lead to new therapeutic approaches for improving sensory processing and cognitive abilities in affected youth.

Who could benefit from this research

Good fit: Ideal candidates for this research are children under 10 years old diagnosed with Fragile X Syndrome.

Not a fit: Patients who do not have Fragile X Syndrome or are over the age of 10 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments that enhance sensory processing and cognitive function in children with Fragile X Syndrome.

How similar studies have performed: While there has been extensive research on Fragile X Syndrome, this specific approach to understanding neurodynamics in children is relatively novel and has not been extensively tested.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.