Understanding brain activity for developing a speech prosthesis
Single-neuron population dynamics in human speech motor cortex for a speech prosthesis
['FUNDING_U01'] · STANFORD UNIVERSITY · NIH-10909969
This study is looking at how the brain helps people with ALS talk, using special technology to understand their brain signals better, so we can create a device that helps them communicate more easily and naturally.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10909969 on ClinicalTrials.gov |
What this research studies
This research investigates how groups of neurons in the speech motor cortex of individuals with amyotrophic lateral sclerosis (ALS) prepare and produce speech. By utilizing advanced brain-computer interface technology, the team aims to decode brain activity related to speech production, enabling the development of a speech prosthesis that allows for faster and more natural communication. The project employs innovative computational methods to analyze neural dynamics, with the goal of achieving conversational speech rates of 120-150 words per minute for those with severe speech and motor impairments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with amyotrophic lateral sclerosis (ALS) who experience severe speech and motor impairments.
Not a fit: Patients without speech or motor impairments, or those with conditions unrelated to speech production, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance communication abilities for individuals with severe speech and motor impairments.
How similar studies have performed: Previous research has shown promising results in using brain-computer interfaces for communication, indicating potential success for this novel approach.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HENDERSON, JAIMIE M — STANFORD UNIVERSITY
- Study coordinator: HENDERSON, JAIMIE M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Amyotrophic Lateral Sclerosis Motor Neuron Disease