Understanding Brain Activity During Deep Brain Stimulation for Parkinson's Disease
Clinical Core
This project aims to understand how brain regions work together during deep brain stimulation in people with Parkinson's disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11174559 on NIH RePORTER |
What this research studies
This project supports a deeper look into how the brain's prefrontal cortex and subthalamic nucleus interact, especially when people with Parkinson's disease are trying to stop an action. We are inviting patients who are already planning to have deep brain stimulation (DBS) surgery for their Parkinson's. Before surgery, participants will complete detailed tests of their thinking and movement abilities. Some participants will also have additional brain activity measurements taken during the DBS lead implantation procedure itself. This helps us learn more about how DBS affects brain function.
Who could benefit from this research
Good fit: Ideal candidates are individuals with Parkinson's disease who are scheduled to undergo deep brain stimulation (DBS) lead implantation surgery.
Not a fit: Patients who are not undergoing deep brain stimulation for Parkinson's disease would not directly benefit from participating in this specific research.
Why it matters
Potential benefit: If successful, this work could lead to a better understanding of how deep brain stimulation helps manage Parkinson's symptoms, potentially improving future treatments.
How similar studies have performed: While deep brain stimulation is a well-established treatment, this specific approach of studying brain activity during the implantation procedure to understand response inhibition is a focused area of ongoing investigation.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Factor, Stewart a — Emory University
- Study coordinator: Factor, Stewart a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.