Understanding bone strength and fragility in people with type 1 diabetes.
Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength
['FUNDING_R01'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-10693825
This study is looking at how type 1 diabetes can affect your bones and make them more likely to break, and it's for people with type 1 diabetes who want to understand how their condition might impact their bone health over time.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10693825 on ClinicalTrials.gov |
What this research studies
This research investigates how type 1 diabetes (T1D) affects bone health, particularly focusing on the risk of fractures. It aims to understand the underlying skeletal issues in T1D patients, including changes in bone density and microarchitecture. By using advanced imaging techniques and measuring glycemic control, the study seeks to identify how these factors contribute to bone fragility. Patients will be monitored over time to assess the impact of diabetes on bone development and strength.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 1 diabetes, particularly those who are young or have had the condition for a significant period.
Not a fit: Patients with type 2 diabetes or those without any form of diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing fractures in individuals with type 1 diabetes.
How similar studies have performed: Previous research has shown promising results in understanding bone health in type 2 diabetes, but this specific focus on type 1 diabetes is relatively novel.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RUBIN, MISHAELA R — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: RUBIN, MISHAELA R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bone Diseases, bone disorder