Understanding Bone Cells to Fight Osteoporosis
Single Cell Dissection of Osteo-blasto/clasto-genic Lineage Cells for Osteoporosis
['FUNDING_OTHER'] · TULANE UNIVERSITY OF LOUISIANA · NIH-11118844
This project explores different types of bone cells to better understand osteoporosis and prevent fractures in older adults.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TULANE UNIVERSITY OF LOUISIANA (nih funded) |
| Locations | 1 site (NEW ORLEANS, UNITED STATES) |
| Trial ID | NIH-11118844 on ClinicalTrials.gov |
What this research studies
Osteoporosis is a common bone disease in aging, leading to weak bones and increased fracture risk, even when bone density is measured. This project aims to look closely at the specific cells that build and break down bone, such as osteoblasts and osteoclasts, in people with osteoporosis. By studying these cells at a very detailed level, including using human bone biopsies and blood samples, we hope to uncover the exact mechanisms behind bone loss and fractures. This advanced approach helps us understand the disease beyond just bone density measurements, paving the way for new prevention strategies.
Who could benefit from this research
Good fit: Patients with osteoporosis, especially those at risk for or who have experienced fractures, could eventually benefit from this research.
Not a fit: Patients without osteoporosis or bone health concerns would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new treatments that specifically target the cells involved in bone breakdown and formation, helping to prevent osteoporosis and fractures.
How similar studies have performed: This project uses advanced single-cell techniques, which are a relatively new and powerful approach to understanding complex diseases like osteoporosis.
Where this research is happening
NEW ORLEANS, UNITED STATES
- TULANE UNIVERSITY OF LOUISIANA — NEW ORLEANS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DENG, HONG-WEN — TULANE UNIVERSITY OF LOUISIANA
- Study coordinator: DENG, HONG-WEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.